|Dr. Mohamed H. Sayegh is currently the Raja N. Khuri Dean of the Faculty of Medicine and Vice President of Medical Affairs at the American University of Beirut. He was appointed in this position in 2009. He was a Professor of Medicine and Pediatrics at Harvard Medical School since 2003, and Director of the Schuster Family Transplantation Research Center at the Brigham and Women’s Hospital and Boston Children’s Hospital. In 2005, he was named the Warren E. Grupe and John P. Merrill Endowed Chair in Transplantation Medicine at Harvard Medical School.
Dr. Sayegh is a world leader in transplantation, renal medicine and transplantation immunobiology research. In his field, he has made substantial and landmark contributions. He has published over 200 original articles in addition to a large number of reviews, editorials and book chapters. He has also edited several books
Dr. Sayegh served as Council Member and President (2000 – 2001) of the American Society of Transplantation (AST). He served as the Chair of the Transplant Advisory Board of the American Society of Nephrology (ASN). He also served as the Chair of the AST Program, Education and Development Committees, as the Chair of the 2005 ASN Program Committee, and the Chair of the Program Committee of the 2006 World Transplant Congress and the 2007 World Congress of Nephrology. He served as co-chair of the Steering Committee of the NIH Immune Tolerance Network and member of the Executive Committee. He also served as Chair of the Steering Committee of the NIH consortium, Clinical Trials in Organ Transplantation (CTOT).
Dr. Sayegh is an elected member of the ASCI, AAP and FRCP. He is also an outstanding mentor. He trained tens of investigators who are active leaders in renal and transplant programs around the world.
Dr. Sayegh is a strong international leader. He served as Chair of the Scientific Advisory Board and member of the Board of Trustees of the Harvard Dubai Foundation. He also serves on the International Advisory Board for the Hamad
Riella LV, Liu T, Yang J, Chock S, Shimizu T, Mfarrej B, Batal I, Xiao X, Sayegh MH, Chandraker A. Deleterious Effect of CTLA4-Ig on a Treg-Dependent Transplant Model. Am J Transplant. 2012 Apr;12(4):846-55. doi: 10.1111/j.1600-6143.2011.03929.x. Epub 2012 Feb 2.
Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N. Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses. Eur J Immunol. 2012 Sep;42(9):2343-53. doi: 10.1002/eji.201242501.
Riella LV, Sayegh MH. T-cell co-stimulatory blockade in transplantation: two steps forward one step back! Expert Opin Biol Ther. 2013 Nov;13(11):1557-68. doi: 10.1517/14712598.2013.845661. Epub 2013 Oct 1.
Azzi JR, Sayegh MH, Mallat SG. Calcineurin Inhibitors: 40 Years Later, Can’t Live Without … J Immunol. 2013 Dec 15;191(12):5785-91. doi: 10.4049/jimmunol.1390055.
Yeung MY, Najafian N, Sayegh MH. Targeting CD28 to prevent transplant rejection. Expert Opin Ther Targets. 2013 Dec 12. [Epub ahead of print]
Senior Lecturer, Harvard Medical School; Schuster
1980 – B.Sc. – American University of Beirut, Beirut, Lebanon
1984 – MD – American University of Beirut, Beirut, Lebanon
Awards & Honors
2008 – First Mentoring Award of the AST
2010 – AST Basic Science Established Investigator Award
2011 & 2012 – Arab Business Power 500 – World’s Most Influential Arabs
2014 – Ben Qurrah Award
- Who We Are
- Basic Research
- Clinical Research